Chemical Safety Data Sheet MSDS / SDS
Revision Date:2025-02-01Revision Number:1
Product identifier
- Product name: Hexane
- CBnumber: CB1852811
- CAS: 110-54-3
- EINECS Number: 203-777-6
- Synonyms: hexane,n-Hexane
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
- Symbol(GHS)
- Signal wordDanger
Precautionary statements
P405 Store locked up.
P403+P235 Store in a well-ventilated place. Keep cool.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P370+P378 In case of fire: Use … for extinction.
P331 Do NOT induce vomiting.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P281 Use personal protective equipment as required.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P273 Avoid release to the environment.
P271 Use only outdoors or in a well-ventilated area.
P270 Do not eat, drink or smoke when using this product.
P264 Wash skin thouroughly after handling.
P264 Wash hands thoroughly after handling.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P240 Ground/bond container and receiving equipment.
P233 Keep container tightly closed.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P202 Do not handle until all safety precautions have been read and understood.
P201 Obtain special instructions before use.
Hazard statements
H411 Toxic to aquatic life with long lasting effects
H401 Toxic to aquatic life
H373 May cause damage to organs through prolonged or repeated exposure
H372 Causes damage to organs through prolonged or repeated exposure
H361 Suspected of damaging fertility or the unborn child
H336 May cause drowsiness or dizziness
H319 Causes serious eye irritation
H315 Causes skin irritation
H304 May be fatal if swallowed and enters airways
H225 Highly Flammable liquid and vapour
Disposal
WARNING.Cancer - https://oehha.ca.gov/proposition-65/chemicals/n-hexane
Substance
- Product name: Hexane
- Synonyms: hexane,n-Hexane
- CAS: 110-54-3
- EC number: 203-777-6
- MF: C6H14
- MW: 86.18
Description of first aid measures
General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: caution if victim vomits. Risk of aspiration! Keep airways free. Pulmonary failure possible after aspiration of vomit. Call a physician immediately.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
Indication of any immediate medical attention and special treatment needed
No data available
Extinguishing media
Suitable extinguishing media
Carbon dioxide (CO2) Foam Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
Special hazards arising from the substance or mixture
Carbon oxides Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
3
| HEALTH | |||
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Environmental precautions
Do not let product enter drains. Risk of explosion.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb?). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Flash back possible over considerable distance.Container explosion may occur under fire conditions. Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limits
Does not contain substances with occupational exposure limits.
Exposure controls
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm Break through time: 480 min
Material tested:Camatril? (KCL 730 / Aldrich Z677442, Size M)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Splash contact Material: Nitrile rubber
Minimum layer thickness: 0,11 mm Break through time: 10 min
Material tested:KCL 741 Dermatril? L
Body Protection
Flame retardant antistatic protective clothing.
Respiratory protection
Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic compounds
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Do not let product enter drains. Risk of explosion.
Exposure limits
TLV-TWA 50 ppm (～175 mg/m3) (ACGIH),500 ppm (～1750 mg/m3) (OSHA); IDLH5000 ppm (NIOSH).
Information on basic physicochemical properties
- Appearancecolorless liquid
- Odourhydrocarbon-like
- Odour Threshold1.5ppm
- pH7,0
- Melting point/freezing pointMelting point/range: -95 °C
- Initial boiling point and boiling range69 °C
- Flash point-22 °C - c.c.
- Evaporation rate15,8
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 8,1 %(V) Lower explosion limit: 1,0 %(V)
- Vapour pressure 100 hPa at 9,8 °C
- Vapour density 3.5 (vs air)
- Relative density0.660 (20/4℃)
- Water solubility0,01 g/l at 25 °C - slightly soluble
- Partition coefficient: n-octanol/waterlog Pow: ca.4 at 20 °C - (Lit.), Potential bioaccumulation
- Autoignition temperature225 °C at 1.013 hPa
- Decomposition temperatureNo data available
- ViscosityViscosity, kinematic: No data available Viscosity, dynamic: 0,3 mPa.s at 25 °C
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
- Henry's Law Constant0.238, 0.413, 0.883, 0.768, and 1.56 at 10, 15, 20, 25, and 30 °C, respectively (EPICS, Ashworthet al., 1988)
- λmaxλ: 200 nm Amax: ≤0.70
λ: 225 nm Amax: ≤0.10
λ: 250 nm Amax: ≤0.01
Other safety information
No data available
Reactivity
Vapors may form explosive mixture with air. Vapors may form explosive mixture with air.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) . The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
Risk of explosion with:
Strong oxidizing agents nitrogen oxides
Violent reactions possible with:
halogens
Risk of ignition or formation of inflammable gases or vapours with:
Peroxides (sodium salt)
Conditions to avoid
Exposure to moisture may affect product quality. Warming.
Incompatible materials
rubber, various plastics
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - male and female - 16.000 mg/kg (OECD Test Guideline 401)
LC50 Inhalation - Rat - 4 h - 172 mg/l Remarks: (RTECS)
LD50 Dermal - Rabbit - male - > 2.000 mg/kg (OECD Test Guideline 402)
Remarks: (ECHA)
Skin corrosion/irritation
Skin - Rabbit
Result: Skin irritation - 24 h (OECD Test Guideline 404)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation - 72 h (OECD Test Guideline 405)
Respiratory or skin sensitization
(OECD Test Guideline 429)
Germ cell mutagenicity
No data available Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: negative
Test Type: dominant lethal test Species: Mouse
Application Route: inhalation (vapor) Result: negative
Remarks: (ECHA)
Carcinogenicity
No data available
Reproductive toxicity
Overexposure may cause reproductive disorder(s) based on tests with laboratory animals. Suspected human reproductive toxicant Suspected of damaging fertility.
Suspected of damaging fertility.
Specific target organ toxicity - single exposure
May cause drowsiness or dizziness. - Central nervous system
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Specific target organ toxicity - repeated exposure
Inhalation - May cause damage to organs through prolonged or repeated exposure. - Nervous system
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Aspiration hazard
May be fatal if swallowed and enters airways.
Aspiration hazard, Aspiration may cause pulmonary edema and pneumonitis.
Toxicity
LC50 (4 hr) in mice by inhalation: 48000 ppm; LD50 orally in rats: 32.0 g/kg (Couri, Milks)
Toxicity
Toxicity to fish
LC50 - Pimephales promelas (fathead minnow) - 2,5 mg/l - 96 h Remarks: (ECOTOX Database)
Toxicity to daphnia and other aquatic invertebrates
EC50 - Daphnia magna (Water flea) - 2,1 mg/l - 48 h Remarks: (Lit.)
Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 98 % - Readily biodegradable. (OECD Test Guideline 301F)
Remarks: (in analogy to similar products)
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Toxics Screening Level
The initial threshold screening level (ITSL) for n-hexane is 700 μg/m3 based on an annual averaging time.
Other adverse effects
No data available
Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
Incompatibilities
May form explosive mixture with air.Contact with strong oxidizers may cause fire and explo sions. Contact with dinitrogen tetraoxide may explode @28℃.Attacks some plastics, rubber and coatings. Mayaccumulate static electrical charges, and may cause ignitionof its vapors.
Waste Disposal
Dissolve or mix the materialwith a combustible solvent and burn in a chemical incinera tor equipped with an afterburner and scrubber. All federal,state, and local environmental regulations must beobserved.
UN number
ADR/RID: 1208 IMDG: 1208
UN proper shipping name
ADR/RID: HEXANES IMDG: HEXANES IATA: Hexanes
Transport hazard class(es)
ADR/RID: 3 IMDG: 3 IATA: 3
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: yes IMDG Marine pollutant: yes IATA: no
Special precautions for user
No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous Chemicals
China Catalog of Hazardous chemicals 2015:Listed. website: https://www.mem.gov.cn/
Measures for Environmental Management of New Chemical Substances
Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/
EC Inventory:Listed.
United States Toxic Substances Control Act (TSCA) Inventory:Listed. website: https://www.epa.gov/
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: https://www.mee.gov.cn/
Philippines Inventory of Chemicals and Chemical Substances (PICCS):Listed. website: https://emb.gov.ph/
European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/
Korea Existing Chemicals List (KECL):Listed. website: http://ncis.nier.go.kr
New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
Other Information
Depending on the degree of exposure, periodic medical examination is suggested.
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.
